5 Reasons to take Magnesium for PMS
It’s estimated that as many as 30% of women can experience moderate to severe PMS, with 5-8% (around 800,000 in the UK) suffering severe PMS. It wasn’t until the early 40’s that PMS became documented as a medical condition and now over 50 years later research has uncovered a collection of 150 symptoms to be associated with this syndrome. Researchers continue to reveal positive results from studies that focus on natural supplements (botanical extracts, vitamins and minerals) which help support hormone balance, recalibrate neurotransmitters and settle down inflammatory prostaglandins all of which underpin the physiology of PMS. One particular nutrient that pops up in many a study is magnesium, here’s why this mineral can help turn down the volume of your monthly premenstrual dramas.
Women with PMS tend to have low magnesium status
During the 7-10 days (luteal phase) leading up to a woman’s period fluctuations in oestrogen and progesterone, nutrient deficiencies and neurotransmitter imbalances all trigger a wide-range of emotional, physical and behavioural symptoms. Science is still discovering the mechanisms behind PMS but magnesium deficiency during the luteal phase is considered to be a contributing factor. One Italian study revealed magnesium deficiency to be common in women suffering from PMS and highlighted, with a 2-month clinical trial, that supplementing 360mg magnesium daily from day 15 to the first day of the menstrual cycle helped lessen menstrual complaints. Another study by Dr Guy Abraham and Joel Hargrove, M.D, also indicated that women with PMS experienced low levels of magnesium in their red blood cells and concluded that rising stress hormones quickly depletes magnesium stores, allowing PMS to escalate.
Liposomal magnesium delivers superior absorption
There are many studies linking magnesium to many different aspects of PMS indicating that magnesium is an in-demand supplement for hormone balance. Many of the clinical studies use magnesium oxide but it is well-known by researchers that this form of magnesium is properly absorbed. Developments in science and technology have enabled liposomal encapsulation technology to create a liposomal form of magnesium a far superior way to deliver a highly absorbable and bioactive magnesium supplement, an ideal choice for PMS sufferers.
1. Headaches and menstrual migraines
Researchers have found a strong connection between oestrogen hormones and migraine headaches, which is why women tend to be more impacted by migraines than men. Episodes of cluster headaches and menstrual migraine (a particular subtype of migraine occurring 2-3 days before menstruation) can be a regular and debilitating factor of PMS for many women. Low levels of oestrogen tend to leave a woman vulnerable to a headaches and migraines but it’s the actual drop in oestrogen that triggers these painful symptoms. Many women who suffer from menstrual migraines find that they become migraine free during pregnancy or after menopause as during these times oestrogen levels remain constant. Among natural products there is some evidence for supplementing with magnesium, phytoestrogens and ginkgolide B, but it’s magnesium that seems to be getting the best results. Researchers have found that a lower migraine threshold may exist because of a magnesium deficiency and that supplementing with magnesium helps to reduce the intensity of migraine pain and improve premenstrual headaches.
2. Cravings and appetite
Around 40% of women with PMS experience increased appetite and cravings for sugar or starchy foods. Studies indicate that these women produce higher amounts of insulin during this phase of their cycle which potentiates blood sugar mis-management. Following a GI or GL diet can be of benefit. Studies indicate that supplementing with magnesium helps support insulin production, manages insulin sensitivity and helps support blood sugar control which in turn helps settle down cravings and appetite.
3. Weight gain and bloating
An estimated 66% of PMS sufferers experience premenstrual weight gain, bloating, breast tenderness and swollen hands, feet or face. Low magnesium in the luteal phase results in increased levels of the corticosteroid hormone aldosterone which is responsible for water balance. High aldosterone levels triggers sodium retention, potentiates further loss of magnesium and fluid retention shortly follows. Reducing stress and embarking on a low or no added sodium (salt) diet is highly recommended and supplementing with magnesium and GLA (Evening Primrose Oil) helps the body rebalance sodium and release water from the body.
In 1998, a double-blind placebo-controlled trail by Dr Ann Walker published in the Journal of Women’s Health, after two months of magnesium supplementation, results revealed reduced premenstrual fluid retention, breast tenderness and bloating by 40% and significantly reduction in weight gain and swelling of the hands and legs.
4. Anxiety and mood swings
By far one of the most common premenstrual issues is anxiety which effects an estimated 80% of women with PMS. This is often accompanied by tension, mood swings, irritability, and nervous tension brought about by raised levels of ‘stimulating’ factors such as oestrogen, serotonin and adrenalin without adequate ‘calming’ dopamine and glutamate. There is a link between low magnesium and the way in which neurotransmitters are released in the brain – when magnesium levels are low the release of dopamine and glutamate is also reduced. Lack of these two neurotransmitters increases anxiety related premenstrual symptoms.
Cutting out caffeine, reducing foods high in saturated fat and lowering stress is a good place to start but supplementing with magnesium is also beneficial. A 2000 study published in the Journal of Women’s Health and Gender-Based Medicine found that the combination of vitamin B6 and magnesium supplementation produced a noticeable synergistic effect which had a positive impact on premenstrual anxiety, mood swings, irritability and nervous tension.
5. Low mood and depression
Another mood related symptom associated for just under 30% of women with PMS is depression often accompanied by tearfulness, feeling overwhelmed, insomnia, clumsiness and feeling withdrawn. Calcium and magnesium work as a team in many areas of health. It’s thought that low magnesium in the luteal phase also creates low calcium and this reduces the release of acetylcholine and glutamate, triggering changes in mood and setting the scene for low serotonin and depression. In a 1991 study published in Obstetrics and Gynaecology, researchers investigated whether magnesium supplementation could improve the mood of women suffering from PMS. The results did indeed reveal that magnesium supplementation generated improvements for those suffering from “negative moods”. Including tryptophan rich mood foods in the diet is also smart idea – bananas, egg white, turkey, chicken, fish, yoghurt, cottage cheese, peanuts, oats and pumpkin seeds.
PMS is a multi-factorial condition influenced by nutritional deficiencies, lifestyle factors, neurotransmitter balance and hormone fluctuations that all women are likely to experience in some point in their life. Making dietary changes, reducing alcohol intake and increasing exercise all help to keep hormones in balance. Supplementing with magnesium offers tremendous support during times when the stress of life unsettles the natural rhythm of your menstrual cycle. This mineral has been shown to be helpful for many of the symptoms associated with PMS.
Author – Susie Debice – Food Scientist and Nutritionist
Facchinetti F, Borella P, Sances G, Fioroni L, Nappi RE, Genazzani AR Oral magnesium successfully relieves premenstrual mood changes.. http://www.ncbi.nlm.nih.gov/pubmed/2067759
Abraham GE, Lubran MM. "Serum and red cell magnesium levels in patients with premenstrual tension." Am J Clin Nutr. 34:2364-6, 1981. www.ajcn.org
Canning, S, Waterman, M and Dye, L (2006) Dietary supplements and herbal remedies for premenstrual syndrome (PMS): a systematic research review of the evidence for their efficacy.Journal of Reproductive and Infant Psychology24(4), 363-378.
Canning, S, Waterman, M and Dye, L (2006) Dietary supplements and herbal remedies for premenstrual syndrome (PMS): a systematic research review of the evidence for their efficacy. Journal of Reproductive and Infant Psychology24(4), 363-378.
Delale OM, Nacharaju VL, Altura BM, Altura BT. Sex steroid hormones modulate serum ionized magnesium and calcium levels throughout the menstrual cycle in women. Fertil Steril. 1998;69:958–62. [PubMed]
James PK. Disorders of magnesium metabolism. In: Fauci AS, Martin JB, editors; Braunwald E, et al., editors. Harrison's principles of internal medicines. 14th ed. Vol 2. USA: McGraw-Hill; 1998. pp. 2263–5.
Mauskop A, Altura BT, Cracco RQ, Altura BM. An open trial of magnesium supplementation for the treatment of migraines and symptoms of premenstrual syndromes in premenopausal women: Effect on serum ionized magnesium level. Neurology. 1997;48:A261–2.
Neurol Sci. 2012 May;33 Suppl 1:S111-5. Premenstrual syndrome and migraine.
Obstet Gynecol. 1991 Aug;78(2):177-81. Oral magnesium successfully relieves premenstrual mood changes.
Rodríguez-Morán M1, Guerrero-Romero F. Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized double-blind controlled trial. Diabetes Care. 2003 Apr;26(4):1147-52.
Seelig MS. Interrelationship of magnesium and estrogen in cardiovascular and bone disorders, eclampsia, migraine and premenstrual syndrome. J Am Coll Nutr. 1993;12:442–58. [PubMed]
Walker AF, De Souza MC, Vickers MF, Abeyasekera S, Collins ML, Trinca LA. Magnesium supplementation alleviates premenstrual symptoms of fluid retention. J Womens Health. 1998 Nov;7(9):1157-65.